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Graphical contents list • CONTENTS LIST PDF (1104 K) | |||
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Publishers Announcement - Chairman of the Executive Board of Editors for Tetrahedron Publications • ANNOUNCEMENT PDF (210 K) | |||
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Tryptamine-based human β3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring • SHORT COMMUNICATION Kazuhiro Mizuno, Masaaki Sawa, Hiroshi Harada, Hirotaka Tateishi, Mayumi Oue, Hiroshi Tsujiuchi, Yasuji Furutani and Shiro Kato SummaryPlus | Full Text + Links | PDF (279 K) | |||
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Tryptamine-based human β3-adrenergic receptor agonists. Part 2: SAR of the methylene derivatives • SHORT COMMUNICATION Masaaki Sawa, Hirotaka Tateishi, Kazuhiro Mizuno, Hiroshi Harada, Mayumi Oue, Hiroshi Tsujiuchi, Yasuji Furutani and Shiro Kato SummaryPlus | Full Text + Links | PDF (271 K) | |||
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Synthesis and antitrypanosomal profile of new functionalized 1,3,4-thiadiazole-2-arylhydrazone derivatives, designed as non-mutagenic megazol analogues • SHORT COMMUNICATION Samir A. Carvalho, Edson F. da Silva, Ricardo M. Santa-Rita, Solange L. de Castro and Carlos A.M. Fraga SummaryPlus | Full Text + Links | PDF (291 K) | |||
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Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants • SHORT COMMUNICATION Clara Cena, Donatella Boschi, Gian Cesare Tron, Kostantin Chegaev, Loretta Lazzarato, Antonella Di Stilo, Manuela Aragno, Roberta Fruttero and Alberto Gasco SummaryPlus | Full Text + Links | PDF (274 K) | |||
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Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists • SHORT COMMUNICATION Guanglin Luo, Gail K. Mattson, Marc A. Bruce, Henry Wong, Brian J. Murphy, Daniel Longhi, Ildiko Antal-Zimanyi and Graham S. Poindexter SummaryPlus | Full Text + Links | PDF (260 K) | |||
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Multidrug resistance reversal activity of permethyl ningalin B amide derivatives • SHORT COMMUNICATION Houchao Tao, Inkyu Hwang and Dale L. Boger SummaryPlus | Full Text + Links | PDF (257 K) | |||
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Synthesis and interfacial behavior of sulfur-containing analogs of lung surfactant dipalmitoyl phosphatidylcholine • SHORT COMMUNICATION Yusuo Chang, Zhengdong Wang, Robert H. Notter, Zhongyi Wang, Long Qu and Adrian L. Schwan SummaryPlus | Full Text + Links | PDF (276 K) | |||
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Identification of a novel non-carbohydrate molecule that binds to the ribosomal A-site RNA • SHORT COMMUNICATION Shawn P. Maddaford, Mina Motamed, Kevin B. Turner, Min Soo K. Choi, Jailall Ramnauth, Suman Rakhit, Robert R. Hudgins, Daniele Fabris and Philip E. Johnson SummaryPlus | Full Text + Links | PDF (533 K) | |||
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α-1-C-Alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile • SHORT COMMUNICATION Guillaume Godin, Philippe Compain, Olivier R. Martin, Kyoko Ikeda, Liang Yu and Naoki Asano SummaryPlus | Full Text + Links | PDF (287 K) | |||
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Isoxazole-3-hydroxamic acid derivatives as peptide deformylase inhibitors and potential antibacterial agents • SHORT COMMUNICATION Patrizia Calí, Lars Nærum, Seema Mukhija and Anders Hjelmencrantz SummaryPlus | Full Text + Links | PDF (299 K) | |||
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Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides • SHORT COMMUNICATION Sabrina Zimmerman, Alessio Innocenti, Angela Casini, James G. Ferry, Andrea Scozzafava and Claudiu T. Supuran SummaryPlus | Full Text + Links | PDF (290 K) | |||
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Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters • SHORT COMMUNICATION Peter C. Meltzer, Duy-Phong Pham-Huu and Bertha K. Madras SummaryPlus | Full Text + Links | PDF (259 K) | |||
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Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists • SHORT COMMUNICATION Deyi Zhang, Dan Kohlman, Joseph Krushinski, Sidney Liang, Bai-Ping Ying, John E. Reilly, Sean R. Dinn, David B. Wainscott, Suzanne Nutter, Wendy Gough et al. SummaryPlus | Full Text + Links | PDF (321 K) | |||
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CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability • SHORT COMMUNICATION Elfatih Elzein, Prabha Ibrahim, Dmitry O. Koltun, Ken Rehder, Kevin D. Shenk, Timothy A. Marquart, Bob Jiang, Xiaofen Li, Reina Natero, Yuan Li et al. SummaryPlus | Full Text + Links | PDF (298 K) | |||
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Tocopherol long chain fatty alcohols decrease the production of TNF-α and NO radicals by activated microglial cells • SHORT COMMUNICATION Thierry Muller, Luc Grandbarbe, Eleonora Morga, Paul Heuschling and Bang Luu SummaryPlus | Full Text + Links | PDF (274 K) | |||
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Synthesis, (1→3)-β-D-glucanase-binding ability and phytoalexin-elicitor activity of (R)-2,3-epoxypropyl (1→3)-β-D-pentaglucoside • SHORT COMMUNICATION Gang-Liang Huang, Xin-Ya Mei, Man-Xi Liu and Tian-Cai Liu SummaryPlus | Full Text + Links | PDF (261 K) | |||
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Fluorescence quenching of parallel-stranded DNA bound ethidium bromide: the effect of 7-deaza-2′-deoxyisoguanosine and 7-halogenated derivatives • SHORT COMMUNICATION Hong Li, Xiaohua Peng and Frank Seela SummaryPlus | Full Text + Links | PDF (301 K) | |||
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Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates • SHORT COMMUNICATION Radhakrishnan Sridhar, Paramasivam T. Perumal, Sundaresan Etti, Guruswamy Shanmugam, Mondikalipudur N. Ponnuswamy, Vaiyapuri R. Prabavathy and Narayanasamy Mathivanan SummaryPlus | Full Text + Links | PDF (291 K) | |||
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Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease • SHORT COMMUNICATION Deliang Duan, Zhengquan Li, Hongpeng Luo, Wei Zhang, Lirong Chen and Xiaojie Xu SummaryPlus | Full Text + Links | PDF (280 K) | |||
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Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies • SHORT COMMUNICATION Dai-Shi Su, M. Kristine Markowitz, Kathy L. Murphy, Bang-Lin Wan, Matthew M. Zrada, C. Meacham Harrell, Stacy S. O’Malley, J. Fred Hess, Rick W. Ransom, Ray S. Chang et al. SummaryPlus | Full Text + Links | PDF (272 K) | |||
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3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors • SHORT COMMUNICATION Ramani R. Ranatunge, Richard A. Earl, David S. Garvey, David R. Janero, L. Gordon Letts, Allison M. Martino, Madhavi G. Murty, Stewart K. Richardson, David J. Schwalb, Delano V. Young and Irina S. Zemtseva SummaryPlus | Full Text + Links | PDF (264 K) | |||
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Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human β-tryptase • SHORT COMMUNICATION Roy J. Vaz, Zhongli Gao, James Pribish, Xin Chen, Julian Levell, Larry Davis, Eva Albert, Maurice Brollo, Antonio Ugolini, Dona M. Cramer et al. SummaryPlus | Full Text + Links | PDF (352 K) | |||
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Synthesis and anticonvulsant activity of new 2-substituted-5- [2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles and 1,2,4-triazoles • SHORT COMMUNICATION Ali Almasirad, Sayyed A. Tabatabai, Mehrdad Faizi, Abbas Kebriaeezadeh, Nazila Mehrabi, Afshin Dalvandi and Abbas Shafiee SummaryPlus | Full Text + Links | PDF (247 K) | |||
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Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors • SHORT COMMUNICATION Ping Chen, Derek Norris, Jagabandhu Das, Steven H. Spergel, John Wityak, Leslie Leith, Rulin Zhao, Bang-Chi Chen, Sidney Pitt, Suhong Pang et al. SummaryPlus | Full Text + Links | PDF (351 K) | |||
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Improving the intein-mediated, site-specific protein biotinylation strategies both in vitro and in vivo • SHORT COMMUNICATION Lay-Pheng Tan, Rina Y.P. Lue, Grace Y.J. Chen and Shao Q. Yao SummaryPlus | Full Text + Links | PDF (317 K) | |||
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Structure-based virtual screening and biological evaluation of potent and selective ADAM12 inhibitors • SHORT COMMUNICATION Myungsok Oh, Isak Im, Yong Jae Lee, Young Hoon Kim, Jeong Hyeok Yoon, Hye Gyeong Park, Shigeki Higashiyama, Yong-Chul Kim and Woo Jin Park SummaryPlus | Full Text + Links | PDF (405 K) | |||
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Novel diarylsulfonylurea derivatives as potent antimitotic agents • SHORT COMMUNICATION Semi Kim, Ji Hyun Park, Sun-Young Koo, Jung In Kim, Min-Hyeung Kim, Ji Eun Kim, Kiwon Jo, Hwan Geun Choi, Sung Bae Lee and Sang-Hun Jung SummaryPlus | Full Text + Links | PDF (274 K) | |||
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Alumina supported potassium permanganate: an efficient reagent for chemoselective dehydrogenation of 2-imidazolines under mild conditions • SHORT COMMUNICATION Mohammad Abdollahi-Alibeik, Iraj Mohammadpoor-Baltork and Mohammad Ali Zolfigol SummaryPlus | Full Text + Links | PDF (261 K) | |||
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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries • SHORT COMMUNICATION Justin J.J. Leahy, Bernard T. Golding, Roger J. Griffin, Ian R. Hardcastle, Caroline Richardson, Laurent Rigoreau and Graeme C.M. Smith SummaryPlus | Full Text + Links | PDF (277 K) | |||
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QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors • SHORT COMMUNICATION S. Balaji, C. Karthikeyan, N.S. Hari Narayana Moorthy and Piyush Trivedi SummaryPlus | Full Text + Links | PDF (278 K) | |||
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Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation • SHORT COMMUNICATION Carlos Jaramillo, J. Eugenio de Diego, Chafiq Hamdouchi, Elizabeth Collins, Heather Keyser, Concha Sánchez-Martı́nez, Miriam del Prado, Bryan Norman, Harold B. Brooks, Scott A. Watkins et al. SummaryPlus | Full Text + Links | PDF (272 K) | |||
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A comparative binding study of modified Bovine Immunodeficiency Virus TAR RNA against its TAT peptide • SHORT COMMUNICATION Jeffrey B.-H. Tok, Lanrong Bi and Shuying Huang SummaryPlus | Full Text + Links | PDF (311 K) | |||
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The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists • SHORT COMMUNICATION Aaron Balog, Mark E. Salvati, Weifang Shan, Arvind Mathur, Leslie W. Leith, Donna D. Wei, Ricardo M. Attar, Jieping Geng, Cheryl A. Rizzo, Chihuei Wang et al. SummaryPlus | Full Text + Links | PDF (341 K) | |||
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Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis • SHORT COMMUNICATION Minmin Wang, Leonard L. Winneroski, Robert J. Ardecky, Robert E. Babine, Dawn A. Brooks, Garret J. Etgen, Darrell R. Hutchison, Raymond F. Kauffman, Aaron Kunkel, Dale E. Mais et al. SummaryPlus | Full Text + Links | PDF (295 K) | |||
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9-cis-Retinoic acid analogues with bulky hydrophobic rings: new RXR-selective agonists • SHORT COMMUNICATION Rosana Alvarez, M. Jesús Vega, Sabrina Kammerer, Aurélie Rossin, Pierre Germain, Hinrich Gronemeyer and Angel R. de Lera SummaryPlus | Full Text + Links | PDF (477 K) | |||
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Evans Blue is an inhibitor of nuclear factor-kappa B (NF-κB)-DNA binding • SHORT COMMUNICATION Rakesh K. Sharma, Masami Otsuka, Vineet Pande, Jun-ichiro Inoue and Maria João Ramos SummaryPlus | Full Text + Links | PDF (450 K) | |||
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Chimeric cyclodepsipeptides as mimetics for the anthelmintic PF1022A • SHORT COMMUNICATION Hubert Dyker, Achim Harder and Jürgen Scherkenbeck SummaryPlus | Full Text + Links | PDF (347 K) | |||
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Corrigendum to “Identification of 4-piperazin-1-yl-quinazoline template based aryl and benzyl thioureas as potent, selective, and orally bioavailable inhibitors of platelet-derived growth factor (PDGF) receptor”: [Bioorg. Med. Chem. Lett. 14 (2004) 4867] • ERRATUM Julie A. Heath, Mukund M. Mehrotra, Shannon Chi, Jin-Chen Yu, Athiwat Hutchaleelaha, Stanley J. Hollenbach, Neil A. Giese, Robert M. Scarborough and Anjali Pandey SummaryPlus | Full Text + Links | PDF (207 K) | |||
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Editorial board • EDITORIAL BOARD PDF (173 K) | |||
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Contributors to this issue • INDEX PDF (189 K) | |||
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Instructions to contributors • PUBLISHER'S NOTE PDF (70 K) | |||
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Author Index 2004 • INDEX PDF (362 K) | |||
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